Before Buy Fosamax
Fosamax is
used to treat and prevent osteoporosis and to treat
Paget's disease. Fosamax is also used to treat
osteoporosis that is caused by treatment with a
corticosteroid.
In
osteoporosis it works by slowing down the process of
old bone being removed, which allows the bone-forming
cells time to rebuild normal bone. FOSAMAX not only
helps prevent the loss of bone but actually helps to
rebuild bone and makes bone less likely to fracture.
Thus, FOSAMAX reverses the progression of
osteoporosis. FOSAMAX starts working on the bone cells
immediately, but measurable effects on bone mass may
not be seen for several months or more.
FOSAMAX
belongs to a group of non-hormonal medicines called
bisphosphonates.
Take Fosamax only as prescribed
Fosamax Possible side effects
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Stop
taking Fosamax and seek emergency medical attention or
contact your doctor immediately if you experience any
of the following serious side effects. An allergic
reaction (difficulty breathing; closing of your throat;
swelling of your lips, tongue, or face; or hives);
Tell your
doctor if you are taking any other medicines,
including medicines that you buy without a
prescription from your pharmacy, supermarket or health
food shop. Some medicines may affect the way other
medicines work.
Some
medicines are likely to interfere with the absorption
of FOSAMAX if taken at the same time. These include:
antacids,
such as Aludrox™, Aludrox Plus™, Amphojel™, Andrews
Effervescent™, Eno™ powder, Gavisgon™, Mylanta™,
Quickeze™, Roter™, Titralac™, Titralac-Sil™, Tums™,
Ural™.
calcium
supplements.vitamins.
Therefore,
take FOSAMAX at least 30 minutes before taking any of
these or other medicines to make sure there is no
problem with absorption. Check with your doctor or
pharmacist if you are not sure whether you are taking
an antacid.
You can
take aspirin while you are being treated with FOSAMAX.
However, both aspirin and FOSAMAX may increase the
chance of stomach upsets.
Your
doctor or pharmacist has more information on medicines
to be careful with or avoid while taking FOSAMAX.
The
symptoms of an Fosamax overdose are unknown, but the
following symptoms might be expected: nausea,
heartburn, pain in your abdomen, other stomach-related
symptoms, muscle cramps, uncontrollable facial
grimacing, seizures, irritability, and abnormal
behavior.
Keep your tablets in the blister pack until it is time
to take them. If you take the tablets out of the
blister pack they may not keep well.
Keep FOSAMAX in a cool dry place where the temperature
stays below 30°C. Do not store it or any other
medicine in the bathroom or near a sink.
Do not leave it in the car or on window sills. Heat
and dampness can destroy some medicines.
Keep it where children cannot reach it. A locked
cupboard at least one-and-a-half metres above the
ground is a good place to store medicines.
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Evista |
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For the treatment and prevention of osteoporosis
in postmenopausal women.
Evista (Raloxifene) is a selective estrogen
receptor modulator (SERM) that belongs to the
benzothiophene class of compounds. The SERM
profile of raloxifene includes estrogen agonist
effects on bone and lipid metabolism but not in
uterine or breast tissues.
In women of childbearing potential. Evista (raloxifene)
therapy during pregnancy may be associated with an
increased risk of congenital defects in the fetus.
evista (Raloxifene) is contraindicated in women
with active or past history of venous
thromboembolic events, including deep vein
thrombosis, pulmonary embolism and retinal vein
thrombosis.
Evista (Raloxifene) is contraindicated in women
known to be hypersensitive to raloxifene or other
constituents of the tablets.
In clinical trials,
raloxifene-treated women had an increased risk of
venous thromboembolism (deep vein thrombosis and
pulmonary embolism). Other venous thromboembolic
events could also occur. A less serious event,
superficial thrombophlebitis, also has been
reported more frequently with raloxifene. The
greatest risk for deep vein thrombosis and
pulmonary embolism occurs during the first 4
months of treatment, and the magnitude of risk is
similar to that associated with use of hormone
replacement therapy. Evista (Raloxifene) should be
discontinued at least 72 hours prior to and during
prolonged immobilization (e.g., postsurgical
recovery, prolonged bed rest) and raloxifene
therapy should be resumed only after the patient
is fully ambulatory. The risk-benefit balance
should be considered in women at risk of
thromboembolic disease for other reasons.
There is no indication for premenopausal use of
Evista (Raloxifene). Safety of Evista (Raloxifene)
in premenopausal women has not been established
and its use is not recommended.
Evista (Raloxifene) was studied, as a single dose,
in Child-Pugh Class A patients with cirrhosis and
serum total bilirubin ranging from 0.6 to 2 mg/dL
(10.3 to 34.2 µmol/L). Plasma raloxifene
concentrations were approximately 2.5 times higher
than in controls and correlated with total
bilirubin concentrations. Safety and efficacy have
not been evaluated further in patients with
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